Marvel
| Name | Super Name | Code | Actions |
|---|---|---|---|
| Spider-Woman (Mattie Franklin) | Spider-Woman | Spider… | Show |
| Spider-X | Spider-X | Spider… | Show |
| Spike | Spike | Spike | Show |
| Spiral | Spiral | Spiral | Show |
| Spirit of '76 | Spirit of '76 | Spirit… | Show |
| Spitfire (New Universe) | Spitfire | Spitfi… | Show |
| Spoilsport | Spoilsport | Spoils… | Show |
| Spoor | Spoor | Spoor | Show |
| Spore | Spore | Spore | Show |
| Spot | Spot | Spot | Show |
| Sputnik | Sputnik | Sputnik | Show |
| Spyder | Spyder | Spyder | Show |
| Spyke | Spyke | Spyke | Show |
| Spymaster | Spymaster | Spymas… | Show |
| Spyne | Spyne | Spyne | Show |
| Squid | Squid | Squid | Show |
| Squirrel Girl | Squirrel Girl | Squirr… | Show |
| Stacy X | Stacy X | Stacy-X | Show |
| Stained Glass Scarlet | Stained Glass Scarlet | Staine… | Show |
| Stallior | Stallior | Stalli… | Show |